Differin

Tough on Acne … But Gentle On You!

  • Differin® (adapalene) 0.1% was the first new topical retinoid treatment for acne since Retin A (tretinoin).
  • Differin® is specifically formulated for the treatment of acne – whiteheads, blackheads, pimples, and pustules.
  • Differin® controls and prevents acne outbreaks by normalizing skin cell formation in the pore and its anti-inflammatory properties.
  • Differin is available in different strengths and formulations:
    1. Differin® Cream 0.1% gm tube
    2. Differin® Gel 0.1% 45 gm tube
    3. Differin® Gel 0.3% 45 gm tube
    4. Differin® Gel 0.3% 45 gm Pump
    • Differin® (adapalene) 0.1% gel and 0.3% gel is a clear, odorless, alcohol-free, fragrance-free gel that works effectively to clear pimples and unclog pores.

    • Differin® is a powerful medicine but it’s also gentle on your skin

    • Quick penetration into the hair follicle where it exerts its anti-inflammatory and comedolytic effects.
    • Prevents whiteheads and blackheads, and reduces the number and severity of acne lesions!
    • More effective and less irritating than many other anti-acne medications.
    • Differin® is Effective and Gentle to your skin!
    • Differin® reduces the number and severity of acne lesions!
    • Available by Doctor’s Prescription only.

    Differin Gel REFILL consultation: For returning Differin Medical Wellness Center clients only.

    IMPORTANT WARNING:  Do no use Differin® if Pregnant or breast feeding.

    IMPORTANT WARNING:   Do Not use is have eczema or seborrhoeic dermatitis.

    MEDICAL WELLNESS CENTER PROVIDES:

    • The easiest, most CONVENIENT, and DISCREET way to receive medical treatment for your most private health needs — All from the PRIVACY and comfort of your home or office!
    • No waiting rooms, No embarrassment, No high fees!
    • RISK-FREE Online Physician Evaluation. Learn if Differin® anti-acne medicine is for you.  If Differin® is not for you, the visit is FREE.

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    • If approved, the Physician Consultation fee is only $49.95 plus processing. You will be issued a Differin® prescription plus two refills with no further consultation charges.
    • Medication purchase NOT required.  Do NOT be fooled by sites that offer free doctor consultation and require medication purchase.
    • You choose the pharmacy.   You can choose most any local US pharmacy.  Select one that accepts your insurance coverage.  The prescription cannot be filled at an internet or online pharmacy, a .COM version of a local pharmacy, a foreign or Canadian pharmacy.
    • EXPRESS service is available.  Your prescription will be called into a local US pharmacy in approximately 24 hours.

       HOW TO REQUEST A PHYSICIAN CONSULTATION FOR A DIFFERIN®  PRESCRIPTION:

    1. First read about Differin® Gel and Differin® Cream and learn more about its indications and  contraindications.
    2. If you do not have any of the contraindications,  read and agree to the Waiver of Liability.
    3. Next, accurately and truthfully complete and submit a medical consultation questionnaire.
    4. Your medial consultation will be reviewed by one of our Physicians.  If approved, you will be issued  aDifferin® prescription with two refills which can be filled at most any local U.S. pharmacy of your choice.
    5. This prescription will provide a minimum of three months of therapy after which another medical consultation is necessary to determine if your response to Differin® and whether you should continue on therapy.
    6. If Differin® is working for you, you will be prescribed Differin® with six refills on each follow-up medical consultation.
    7. This physician evaluation is RISK-FREEIf Differin® prescription is not appropriate for you there is NO CHARGE. The initial consultation fee for the physician evaluation is only $49.95 plus processing.
    8. We offer Express service option: Your prescription is called into most any local United States pharmacy of your choice within approximately 24 hours or less.
    9. If you have any health concerns in any way, you should contact your own physician for further advice.

    Tips for surviving acne:

      • Cleanse your face regularly with a mild NON-soap cleanser such as Cetaphil, but not too often. No more than twice a day.
      • NEVER squeeze, pick, or pinch acne pimples or use sharp objects on them.
      • This will only contribute to infection, inflammation, and scarring.
      • If you use cosmetics or moisturizers, be sure they are “non-comedogenic” or “non-acnegenic.”
      • Use oil-free cosmetics and moisturizers.
      • Be patient as it can take several weeks or longer for your acne to clear and even longer for large pimples to fade completely.
      • Use your acne medications regularly and consistently to help the formation of new pimples. Remember, once a pimple starts, it can stick around for weeks or months. It is easier to prevent new pimples from forming than to have to wait for existing ones to clear.
      • Follow your doctor’s recommendations in caring for your skin.
      • If your acne does not respond to treatment after 12 weeks consult your own physician immediately.
      • In order for Differin Gel to be effective one must use it consistently as directed. If you get severe irritation or blistering discontinue use and consult your own physician.

       Differin® Q&A

      WHAT IS DIFFERIN®?

      Differin® (adapalene) is the first new topical treatment for acne since Retin A (tretinoin) was introduced in 1972.  Adapalene is a synthetic retinoid analogue  and it functions in a manner similar to that of tretinoin but demonstrates greater effectiveness and is gentler on the skin.   In medical studies Differin® reduces the number and severity of acne lesions after 12 weeks of therapy. Differin® has demonstrated greater effectiveness than the highest strength of topic Retin-A gel.  Furthermore, patients on Differin® experience significantly less skin dryness and skin irritation than those using Retin-A.

      WHAT IS ACNE?

      Acne is a disorder of the skin’s oil glands (sebaceous glands) located at the base of the hair follicle. Outbreaks of varying degrees of acne lesions, commonly referred to as pimples and zits, are due to plugged pores. Acne lesions occur most commonly on areas that have the highest concentration of sebaceous glands: face, neck, upper back, chest and shoulders.

      When these oil glands become overactive and plug up the primary lesion of acne, comedones, commonly referred to as a blackheads (open comedones) or whiteheads (closed comedones) develop. Comedones are non inflammatory lesions characteristic of Grade I acne. The classic “pimple” develops as the bacteria (Propionibacterium acnes) beneath the skin thrive on this oil and produce redness and pus, Grade II – Grade III. As this infection spreads into the deeper layers of the skin pustules and cysts can develop, Grade IV. Although acne is not a serious health threat, if not treated acne can cause permanent scarring.

      Differin Gel is a recommended topical treatment of Grade I – Grade III acne Vulgaris. Epiduo™ Gel is not indicated for those with Grade IV Acne where pustules and cysts predominate – severe pustular and deep cystic nodular acne known as Acne Conglobulata.

       

      WHAT ARE THE DIFFERENT GRADES OF ACNE?

      Acne varies in severity from some whiteheads and blackheads (Grade I) to severe pustular and cystic acne (Grade IV). Differin® is a recommended topical treatment of Grade I – Grade III acne vulgaris. Differin® is not indicated for those with Grade IV Acne where pustules and cysts predominate – severe pustular and deep cystic nodular acne is known as Acne Conglobulata.

       

      ACNE- GRADE I: Comedones (whiteheads & blackheads) only 

      Grade One Acne Differin® prescriptionGrade I Acne Differin® prescriptionAcne Grade I Aczone Gel

      Grade I Acne is characterized by open comedones and closed comedones commonly referred to as blackheads (open comedones) and whiteheads (closed comedones). There are no inflammatory lesions, making scarring unlikely.

      ACNE GRADE II:  Comedones, papules and a few pastules

      Grade II Acne Online Differin®prescriptionAcne Grade II Online Differin® prescription Differin®l prescription online for Grade II acne

      GRADE II Acne is characterized by mainly open and closed comedones (blackheads and whiteheads) and papules, with some pustules. Papules  are the classic “pimple” that develops when bacteria beneath the skin produces redness and pus.  These papules are small, granular lesions associated with the destruction of the epithelial lining of the sebaceous hair follicle wall. These may be inflammatory and scarring generally does not result.

      ACNE- GRADE III: Comedones, papules, pustules, few nodules

      Grade II Acne Online Differin® prescription 

      Grade III acne is characterized by papules and pustules. Pustules have a yellowish, blister-like appearance and result from the breakdown of the follicle wall. Nodules are small, solid nodes detectable by touch. Scarring may be likely.

       

      ACNE- GRADE IV:

      Grade IV acne

      GRADE IV: acne is characterized by a few comedones, some papules, and many pustules, nodules, cysts, and abscesses. This is a severe but not very common form of acne known as acne conglobata. Scarring exists and is generally severe. Differin® is NOT prescribed for this condition as you need direct dermatologist supervision. You need to consult your doctor or dermatologist.

      WHO IS SUSCEPTIBLE TO ACNE?  ADULTS & TEENAGERS!

      Acne is the most common skin disease affecting over 70 million people worldwide, over 17 million in the United States. Acne is not just an adolescent condition. Acne usually begins around puberty due to an increase in hormonal levels and usually tends to resolve within 10 years, but there is an increasing number of people, mostly women, who are being troubled by acne later in life. Acne affects nearly 85% of all adolescents and teens are troubled with acne. Nearly 5 million American adults suffer from acne and women are twice as likely as men to develop adult acne. In women, an increase in hormones prior to their menstrual cycle tends to make acne worse.

       

      WHY DO I NEED TO TREAT ACNE?

      Although acne is not a serious life threatening condition, if not treated acne can cause permanent scarring.  Grade III and IV Acne with deep pustules and cysts result in scarring.

       

      WHO QUALIFIES FOR AN ONLINE DIFFERIN® CONSULTATION?

      If you are 18 years or older, not pregnant or breast feeding, and have been diagnosed by a physician with acne vulgaris – Grade I, II or III your are eligible for an online Differin® physician consultation. Differin® is NOT indicated for Grade IV. If you have Grade IV acne you need to see your physician or dermatologist.

       

      HOW DOES DIFFERIN® WORK TO TREAT ACNE?

      Differin® (adapalene) 0.1% is applied directly to the face or the affected area and it works deep inside your pores reducing controlling improper skin buildup and reducing the inflammatory component of acne. Acne forms when hormones trigger an abnormal accumulation of skin cells and an overproduction of oil in skin pores. The pores (hair follicle) become clogged, forming a plug, and enable bacteria to grow and comedones (whiteheads & blackheads) and papules and pustules and nodules (pimples) develop. It works by controlling the improper accumulation of skin cells that plug the pores and helping skin cells shed normally rather than allowing them to accumulate in pores. Differin® is effective at clearing up pimples, whiteheads and blackheads by clearing the pores of oil-blocking skin cells.

      WHAT ARE THE DIFFERENCE BETWEEN DIFFERIN® GEL, SOLUTION  & CREAM?

      Differin® comes in a gel, solution and cream formulated specifically for the special needs of people with acne.

      • Differin® (adapalene gel) Gel 0.1% and 0.3% is a clear, odorless, oil-free and alcohol-free gel that is specifically designed to meet the needs of most patients. It’s a light gel that feels nice on your skin. It doesn’t contain alcohol which can overly dry your skin and it isn’t oily so it won’t leave any greasy residue behind. The 0.3% Gel comes in a 45gm tube or a convenient 45gm Pump.
      • Differin® (adapalene) Cream 0.1% is an odorless and elegant cream designed specifically designed for patients with sensitive skin who need the power of Differin® in a product that their skin can tolerate. This cream absorbs quickly and easily.
      • Differin® (adapalene) Solution 0.1% contains alcohol and is harsher on the skin and more irritating than either the Gel or Cream. This solution is designed more for younger acne patients with very oils skin and truncal acne and it causes MORE irritation than the gel. The solution comes in an Dab-o-matic applicator or single use Pledgets. Due to the more severe side effects and skin irritation resulting from Differin® solution over the Gel or Cream, we DO NOT prescribe Differin® in solution form over the internet!

      WHEN & FOR HOW OFTEN DO I USE DIFFERIN®?

      Differin® is applied to the skin once a day in the evening before bedtime. Differin® must be used consistently as there is no instant or immediate cure for acne.
      Step 1:  Wash the affected area with a mild nonsoap cleanser
      Step 2:  Pat dry with a soft towel to remove excess water.  Never rub harshly.
      Step 3:  Apply a pea-size amount of Gel or Cream. Spread a thin film evenly over the entire face, avoiding the eyes, lips, angles of the nose, and mucous membranes. Try not to touch the treated areas.
      Step 4: Wash your hands

      With proper care and treatment, acne can be controlled and scarring may be prevented. Use Differin® exactly as prescribed. Applying excessive amounts or using the formulation more than once a day will not produce better results and may cause severe redness, peeling and discomfort.

       

      HOW LONG BEFORE I SEE RESULTS?

      Differin® affect cell accumulation and reduces the inflammatory response within the pores. During the first 1 – 2 weeks of treatment, your acne may appear to get worse. Don’t despair. This is expected and just means that the medication is working on pimples that you may not yet see. Continue using the product. It can take up 8 – 12 weeks before you start to see improvement and with continued use further improvement is expected. How long it takes to clear your pimples will depend on the severity of your acne. Larger pimples or more severe cases of acne may take longer to clear than milder cases. Use Differin® consistently even after your acne goes away on areas where outbreaks usually occur for prevention. If your acne does not start to improve within 12 weeks, check with your own doctor.

       

      HOW DOES DIFFERIN® DIFFER FROM RETIN-A  & OTHER RETINOIC ACIDS?

      Differin® is a formulation of adapalene which is a new synthetic retinoid analogue that has demonstrated greater effectiveness than the highest strength of topical Retin- A gel or other retinoid topical products. In addition Differin® is MUCH GENTLER to your skin than other retinoid products with significantly less skin dryness and skin irritation. Adapalene functions in a manner similar to that of retinoid products but with greater effectiveness and less irritating side effects. Retinoid therapy has been recognized for more than 20 years to be excellent acne therapy, but its usage has been limited in many patients due to it’s side effects. Differin® has been shown to be more effective with better tolerance and less side effects Benefits of Differin®:

      • excellent tolerability
      • quick penetration into hair follicles where it can exert its anti-inflammatory and comedolytic effects
      • Differin® Gel and Cream are both formulated specifically for the special needs of patients with acne.

       

      WHAT FACTORS PLAY A PREDISPOSING OR EXACERBATING ROLE IN ACNE?

      Heredity plays a very important role. Acne is a hereditary disease. Most people with acne know someone in the family that also had it at sometime. If both parents had severe acne, you too will have significant acne. If nobody in your family has bad acne, chances are you will not get severe acne. The acne skin that has overactive sebaceous glands with increased cellular and oil production is inherited and these are the precise factors that Differin® work against and controls.

      Hormones play a role and during adolescence those prone to acne will begin to break out. Usually the acne outbreaks subside within 10 years but may continue on into adulthood. Women are especially prone to outbreaks during the hormonal changes during their menstrual  cycle. It is the male hormone in both males and females that is the cause the sebaceous oil gland to become overactive and result in acne outbreaks.

      Stress:  During stressful times such as school exams, deadlines etc the male hormone in both males and females rise resulting in increased acne flare-ups.

      Bacteria:  The bacterium, Propionibacterium acnes, which grows beneath the skin thrives on the oil in the sebaceous gland and plays an important role in the changes of noninflammatory acne to inflammatory acne.

       

      DO DIET or BAD HABITS CAUSE ACNE OUTBREAKS?  MYTH or FACT?

      From the beginning of time poor diet and a number of bad habits have been blamed as the leading causes for acne outbreaks. But the truth is that they have little or nothing to do with it. And while proper nutrition, exercise and plenty of sleep are great for general health, they do not have anything to do with preventing or curing acne.

      Myth: People who don’t wash enough get acne. If your skin is clean it won’t break out.

      FACT:  This is not true. Over-washing may actually irritate you skin.  The blackheads are  pores clogged with oil and an accumulation of skin cells within the pore, not dirt. Bacteria that reside under the skin (not on the surface of the skin) in the pores cause the inflammation of the hair follicles that contribute to the formation of pimples.

      Myth: What you eat plays a big part in how your skin looks. For example, chocolate and greasy, fired “fast foods” cause your skin to break out or make your complexion worse.

      FACT Food is neither the cause nor the cure for acne, yet many acne sufferers have followed difficult diets for years. For the most part, the food that you eat has little to do with acne outbreaks. The notion that chocolate or greasy, fried fast foods lead to greasy skin is incorrect. The oils you ingest has nothing to do with oil manufactured in your skin by the sebaceous gland. Although chocolate and greasy foods causing acne is a myth, it is possible for an individual to have a unique sensitivity to a certain food. If you believe a particular food causes your acne to flare up, avoid it for at least 60 days and see if your acne improves.

       

      CAN DIFFERIN® BE USED ALONG WITH OTHER SKIN MEDICATIONS OR PRODUCTS?

      • Differin® should not be used along with other anti-acne products containing Retinoid, retinoic acid, trinitoin or Vitamin A such as Retin-A, Retinol, Renova.
      • Differin® should not be used with any skin products containing sulfur, resorcinol or salicylic acid.
      • Differin® should not be used with any abrasive or medicated soaps, astringents, alcohol, lime, or witch-hazel products, or any products than can be drying or irritating to the skin.
      • Differin® should not be used with products containing alpha hydroxy, hydroxy or glycolic acid containing products.
      • Differin® can not be used with any peeling agents, glycolic peels, chemical peels or laser peels.
      • Differin® should not be used with benzoyl peroxide, Skinoren or Azelex as they may be drying or irritating.
      • Differin® can be used with topical anti-acne antibiotic treatments such as erythromycin, clindamycin, Dalacin-T or Cleocin-T if applied in the morning and Differin® is applied in the evening before bedtime. The two can not be applied at the same time. Always check with your prescribing doctor before adding Differin®.
      • Differin® can be used with non-oily noncomedogenic moisturizers and cosmetics.

       

      WHAT KIND OF CLEANSER SHOULD I USE WHILE USING DIFFERIN®?

      Acne is not caused by dirt, and too much vigorous washing can dry your skin or even aggravate your acne. Cleansing twice a day is sufficient with a mild, NONSOAP, fragrance-free cleanser such as Cetaphil® Cleansing Bars or Cetaphil® Gentle Skin Cleansers. Do not use medicated soaps and cleansers that have a strong drying affect.

       

      CAN I WEAR MAKEUP WHILE USING DIFFERIN®?

      Yes, you can wear makeup. Do NOT use oil-based makeup or cosmetics that have an abrasive, drying or peeling action. Make sure than when you buy cosmetics, moisturizers or any other skin products they are labeled as “noncomedogenic” or “nonacnegenic.” This means that they are not likely to cause whiteheads or blackheads.

       

      WHILE USING DIFFERIN® SHOULD I USE A MOISTURIZER?

      Since acne medication including Differin® can be drying, it may be helpful to use a moisturizer. Use a mild, fragrance-free, non-oily, non-irritating moisturizer that is noncomedogenic. Make sure your moisturizer does NOT contain alpha hydroxy or glycolic acids, retinoid, retinol, vitamin A, trinitoin, or any other drying or irritating agent. Cetaphil® Moisturizers are a possible choice.

       

      WHILE TAKING DIFFERIN® CAN I USE TANNING BEDS OR SUNBATHE?

      When using Differin®, you must avoid all sun exposure possible because Differin® makes your skin more sensitive to sunlight. Do NOT sunbathe. Do NOT use tanning beds or sunlamps. When using Differin® you must ALWAYS take proper precautions to protect sun exposed skin using sunblock, hats and protective clothing. Never apply Differin® to sunburned skin!

       

      WHAT ARE THE SIDE EFFECTS of Differin®?

      Differin® is gentle on the skin, but 10-40% of patients do experience some skin irritation which is reversible when the treatment is discontinued or reduced in frequency. The most common side effects are erythema (redness), drying, scaling, irritation, pruritis (itching), burning, stinging and acne flare-up. Most of these reactions are not severe and occur during the first month of treatment and resolve with continued use. About 20% of patients experience a feeling of stinging, pruritis or burning immediately after application. During the initial weeks of therapy if these adverse effects are too bothersome, you may try decreasing the frequency of use and as your tolerance improves increase frequency to recommended once a day usage.

      If severe irritation occurs, blistering, crusting or swelling discontinue use and check with your physician.

       

      WHO SHOULD NOT USE DIFFERIN®?

      • Do NOT use Differin® if you are pregnant or attempting to become pregnant. Differin® MAY HARM an unborn baby.
      • Do NOT use Differin® if you are breast feeding.
      • Differin® is NOT to be used in children or anyone under the age of 18. Not approved for pediatric use below age 12 but we do not prescribe for anyone less than 18 year of age online.

       

      In order to proceed to the medical consultation, you must go to the next section and read the complete list of contraindications. Then you must verify that you do not have any of the contraindications, you are not pregnant and are not breast feeding. 


      Before Proceeding to the Medical Consultation Form  please read

      CONTRAINDICATIONS, PRECAUTIONS and WARNINGS
      and accept the Waiver of Liability

      CONTRAINDICATIONS

      Differin® is the first new topical retinoid treatment for specifically designed acne and it’s gentle one the skin.Differin® use is CONTRAINDICATED and must NOT be used in anyone with the following conditions:

      • Do NOT use Differin® if you are pregnant or attempting to become pregnant. Differin® (adapalene) has been show to cause fetal changes in animal studies, and may harm unborn baby.
      • Do NOT use Differin® if you are breast feeding.
      • Do NOT use Differin®  if you are allergic  or sensitive to Adapalene any of the ingredients.
        • Differin Gel contains: carbomer 980, propylene glycol, poloxamer, disodium edetate, methyl hydroxybenzoate, phenoxyethanol, sodium hydroxide and purified water.
        • Differin® Cream contains carbomer 934P, cyclomethicone, edetate disodium, glycerin, methyl glucose sesquistearate, methylparaben, PEG-20 methyl glucose sesquistearate, phenoxyethanol, propylparaben, purified water, squalane, and trolamine.
      • Differin® is contraindicated if you have severe case of acne Grade IV with pustules and cysts.
      • Do NOT use Differin® if you have eczema, sebbhoreic dermatitis or psoriasis skin conditions.
      • Do NOT use Differin® on broken or cut skin, abrasions, or sunburned skin.
      • Do NOT use Differin® with any skin products containing sulfur, resorcinol or salicylic acid.
      • Do NOT use Differin® if you are being treated with Accutane, Retin-A, Retin-A Micro, Tretinoin, isotretinoin preparation or other Vitamin a retinoid products.
      • Differin® is NOT approved for pediatric use for children under 12.
      • We do NOT prescribe Differin® to anyone under the age of 18.

       

      IMPORTANT PRECAUTIONS AND WARNINGS 

      • Differin® is ONLY approved for external TOPICAL use on the face, neck, chest, upper back and shoulders. Avoid contact with eyes, lips, angels of the nose and mucous membranes. Flush with water and seek medical attention!
      • Differin® makes you more sensitive to sunlight. Avoid all sun exposure, including tanning beds and sunlamps. Always use sunscreen and protective clothing over treated areas.
      • Do NOT use medicated soaps or abrasive cleansers. Use mild, non-soap, fragrance free cleansers like Cetaphil® Cleansing Bars or Cetaphil® Gentle Skin Cleanser.
      • Do NOT combine Differin® with any other retinoid, retinoic acid, trenitoin, or Vitamin a product such as Renova, Retin-A, Retinol etc.
      • Do NOT use Differin® with any acohol-containing products, astringents, witch hazel or lime that may be drying to your skin.
      • Do NOT have any cosmetic peels, glycolic peels or laser procedures while using Differin®.
      • Do NOT use Differin® with any alpha hydroxy, hydroxy or glycolic acid products.
      • Do NOT use any oil-based cosmetics or oil-based moisturizers. Make sure all cosmetics and moisturizer you use are noncomedogenic or nonacnegenic.
      • Do NOT use Differin® with any skin products containing sulfur, resorcinol or salicylic acid.
      • Do NOT use Differin® with any skin products containing benzoyl peroxide, Skinoren or Azelex as they may be drying or irritating.
      • Avoid waxing or other depilatory methods on Differin® treated skin.
      • Avoid exposure to cold and windy weather which map be irritating to patients under treatment.
      • If the you are experiencing skin irritation you may try decreasing the frequency of application until you can tolerate a once daily application. If the skin irritation is severe with blistering and crusting DISCONTINUE USE and seek immediate medical attention from your regular physician.
      • If you do not see any improvement or your condition continues to worsen after 12 weeks of treatment, discontinue use and see your own physician for evaluation and treatment.
      • Differin® is to be used as part of a skin care regimen and needs to be used continuously to prevent acne outbreaks and scarring.
      • Keep away from children.

      ADVERSE REACTIONS – SIDE EFFECTS:

      • The  majority of patients using Differin®  experience minimal side effects. Between 10 -40% of patients experience erythema (redness), drying, scaling, irritation, pruritis (itching), burning, stinging and acne flare-ups.   About 20% of patients experience a feeling of stinging, pruritis or burning immediately after application.  These side effects usually abate during continued use, an all side effects are reversible when the treatment is discontinued or reduced.  If  you experience increasing redness, swelling, blistering or crusting, stop use of Differin® and contact your doctor.
      • If you get the medication in your eyes, rinse immediately with water and contact your regular physician!
      • There are NO systemic effects when used appropriately.

       

      IMPORTANT PATIENT INSTRUCTIONS

      How to apply Differin® Gel 0.1% or Differin® Cream 0.1% – Easy to Use:

      1. Step 1: Wash. Right before bedtime, gently cleanse the entire face and acne areas with a mild non-soap cleanser such as Cetaphil®.
      2. Step 2: Dry. Pat skin dry gently with a soft towel to remove excess water. Never rub harshly, as this may irritate the skin.
      3. Step 3: Apply a pea-size amount of Differin® gel or Differin® cream to your face and other acne areas. Spread a thin film over the entire face avoiding the eyes, lips, angles of the nose and mucous membranes. You may be tempted to use more than a dot, thinking it will work faster or better on your acne. Don’t use too much. It won’t work better and may increase the potential for irritation.
      4. Apply Differin® only once a day before bedtime
      5. About 20% of patients feeling a burning or tingling sensation immediately after application.
      6. Between 10 -40% of patients experience some drying, stinging, burning etc, but if you experience a severe irritation decrease frequency of use until you can build up a tolerance. If you experience blistering or crusting discontinue use and seek medical attention from your own physician.
      7. It’s WORTH THE WAIT: During the first 2 weeks of treatment you may see an increase in acne, but  by treatment week  8 – 12 you should start to see improvement in your acne. If you do not see any improvement by week 12, discontinue use and see your own doctor.
      8. Differin® must be used consistently in order to prevent and control acne outbreaks. Use it even after your acne goes away on areas where you usually have acne outbreaks.

      I DO NOT HAVE ANY OF THE ABOVE CONTRAINDICATIONS:

      In order for Medical Wellness Center Physicians to provide you with the best care, you need to reply honesty to all questions and you need to understand any and all contraindications, risks and side effects associated with Differin® Gel 0.1% and Differin® Cream 0.1%.

      By accepting “I Agree” means that you have read the above contraindication, precautions and warnings and honestly acknowledge that you do not have any of the above contraindications to Differin® therapy. Also, that I am aware of the side effects. I fully understand that Differin® is indicated only for Grade I – Grade III acne. Differin® is contraindicated in anyone who is hypersensitive to adapalene or any of its components, has eczema, sebborheic dermatitis, psoriasis or is under age 18. I understand that it is solely my responsibility to seek diagnostic and medical treatment for any underlying medical conditions from my own regular primary care physician.

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        MEDICAL WELLNESS CENTER: ONLINE HEALTH CARE & PRESCRIPTIONS

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        IMPORTANT NOTE: This is a summary and does not contain all possible information about this product. For complete information about this product or your specific health needs, ask your health care professional. Always seek the advice of your health care professional if you have any questions about this product or your medical condition. This information is not intended as individual medical advice and does not substitute for the knowledge and judgment of your health care professional. This information does not contain any assurances that this product is safe, effective, or appropriate for you.